St Louis to Cleveland road trip: Distance, drive time & best stops

The best road trip stops on the St Louis to Cleveland drive are Casey IL, Indianapolis and Columbus OH. The distance from St Louis to Cleveland is 562 miles, with an 8h22m driving time.

Planning a St Louis to Cleveland road trip itinerary

The drive from St Louis to Cleveland takes you from the Mississippi River in Missouri to Lake Erie in Ohio. And there are plenty of things to do on the way.

Good St Louis experiences include true crime walking tours and small group tours that include going to the top of the St Louis Arch and a Mississippi River cruise.

There are several strong attractions in Cleveland, including the Cleveland History Center. But the big stand out is the Rock N Roll Hall of Fame. It’s an extremely reverent trawl through rock ‘n roll history, looking at the origins and development of the genre. There’s a massive amount of memorabilia, with sections devoted to several Hall of Fame inductees.

The Rock N Roll Hall of Fame is dense, detailed and capable of sucking up the best part of a day.

Alternatively, Cleveland tour options focus on neighbourhood food scenes, the city’s best craft breweries and Downtown’s public art.

St Louis to Cleveland distance and driving time

By car, the distance from St Louis to Cleveland is 562 miles. You can expect a driving time of around eight hours and 22 minutes. The quickest route largely follows the I-70 and I-71.

The best stops to add to a St Louis to Cleveland road trip itinerary are Casey IL, Indianapolis and Columbus OH.

St Louis to Cleveland road trip attractions: Casey, Illinois

Casey, Illinois, is possibly the silliest town in the US. It has decided that its niche is going to be making Big Things, and displaying them by the side of the road. That means you can see the World’s Largest Rocking Chair, the World’s Largest Pitchfork, the World’s Largest Golf Tee and several other record-breakers.

Not all are officially the biggest on the planet, but you can also see the Big Rocking Horse, the Big Taco and the Big Anvil.

Best stops between St Louis and Cleveland: Indianapolis

The capital of Indiana marries big city energy with country charm.

Top attractions in Indianapolis include the Indianapolis Motor Speedway Museum and the Children’s Museum of Indianapolis.

Worthwhile Indianapolis experiences include a Fountain Square food tour and a walking tour around the city’s highlights.

St Louis to Cleveland drive: Columbus, Ohio

In Columbus, a three day attractions pass covers most of the top sights. These include the Columbus Museum of Art, Columbus Zoo and Aquarium, Franklin Park Conservatory and Botanical Gardens and the National Veterans Memorial and Museum. For other Columbus experiences, try scavenger hunts, a town tour aboard the Trolley Pub and the Legoland Discovery Center.

The Rock N Roll Hall of Fame in Cleveland, Ohio.
The Rock N Roll Hall of Fame in Cleveland, Ohio. Photo by David Whitley/ Best3Stops.

More Cleveland road trips

Cleveland to Atlanta | Cleveland to Baltimore | Cleveland to Buffalo | Cleveland to Chicago | Cincinnati to Cleveland | Columbus to Cleveland | Dallas to Cleveland | Dayton to Cleveland | Cleveland to Detroit | Indianapolis to Cleveland | Louisville to Cleveland | Cleveland to Nashville | Cleveland to New Orleans | Cleveland to Niagara Falls | Cleveland to Philadelphia | Pittsburgh to Cleveland | Toledo to Cleveland.

More St Louis road trips

St Louis to Atlanta | Boston to St Louis | St Louis to Branson MO | St Louis to Chicago | St Louis to Columbus | Dallas to St Louis | Denver to St Louis | Detroit to St Louis | Houston to St Louis | Indianapolis to St Louis | St Louis to Joplin MO | Kansas City to St Louis | St Louis to Knoxville | St Louis to Milwaukee | Nashville to St Louis | St Louis to New York City | St Louis to Oklahoma City | Omaha to St Louis | St Louis to Philadelphia | St Louis to Pittsburgh | St Louis to Springfield MO | St Louis to Tampa | St Louis to Tulsa | St Louis to Washington DC | Wichita to St Louis.