Tucson to Sedona road trip: Best stops, distance & drive time
The best road trip stops on the Tucson to Sedona drive are Casa Grande, Phoenix and Camp Verde. The distance from Tucson to Sedona by car is 228 miles, with a 3h28m driving time.
Planning a Tucson to Sedona road trip itinerary
The Tucson to Sedona drive connects two of the most attractive destinations in Arizona.
Tucson is often used as a base for exploring the Sonoran Desert. But it’s a proper city with an arty streak, a Spanish-tinged history and excellent Mexican food.
Top Tucson experiences include exploring the city’s many murals, taking a self-guided audio tour through Saguaro National Park and canyoneering at Mt Lemmon.
There are also several good bike tours you can do in and around Tucson. Choose from a history-focused ride through the city, e-biking in Saguaro National Park and taco-tasting on two wheels.
For resort-style accommodation in Tucson, take a look at the impressive Casino Del Sol Resort. To stay downtown, within walking distance of several restaurants, try the Leo Kent Hotel.
Desert town Sedona sits in an inspirational setting amid red rock buttes, canyons and forest. It’s no wonder so many artists choose to live there. Fantastic spots around Sedona include Cathedral Rock, Courthouse Butte and Red Rock Crossing.
The surrounding desert trails and state parks are magnificent for hiking and biking. You can also explore on a scenic helicopter flight, outback Jeep tour, guided ATV adventure or e-biking at Cathedral Rock.
Other Sedona experiences include Verde Valley wine tours, Jeep tours of the mystical Sedona vortexes, glassblowing workshops and nighttime stargazing sessions.
For great Sedona accommodation that makes the most of the views, try the Sky Ranch Lodge or Amara Resort.
Tucson to Sedona distance and driving time
By car, the distance from Tucson to Sedona is 228 miles. You can expect a driving time of around three hours and 28 minutes. The quickest route is largely up the I-10 and I-17.
The best stops to add to a Tucson to Sedona road trip itinerary are Casa Grande, Phoenix and Camp Verde.
For more suggestions, read the guides to the Tucson to Phoenix drive and Phoenix to Sedona drive.
Tucson to Sedona drive: Casa Grande AZ
In Casa Grande, you can learn about local history at the Museum of Casa Grande. However, the Casa Grande Ruins National Monument provides a far more evocative history lesson. Here, the remains of a great house and farming sites belonging to the Ancestral Sonoran People are preserved.
For something more quirky, head to the Casa Grande Neon Sign Park, where unwanted neon signs spend their retirement.
Tucson to Sedona road trip attractions: Phoenix, Arizona
A stay in Phoenix is at its best when you explore the surrounding Sonoran Desert. That might be in a hot air balloon flight, on an ATV tour or on a guided sunset hiking adventure. You can also do day tours along the Apache Trail.
For other Phoenix experiences, try a downtown food tour, a street art tour or a spooky nighttime ghost walk.
Attractions that you might wish to buy advance include cell phone-friendly tickets for include Phoenix Zoo, the Sea Life aquarium or a drunk Shakespeare performance.
For Phoenix accommodation options with a bit of character, try the art-splashed Foundre or the resort-like Raintree at Phoenix South Mountain Preserve.
Best stops between Tucson and Sedona: Camp Verde, Arizona
Camp Verde is an all-action kind of place. Great Camp Verde activities include tackling the Verde River in an inflatable kayak, horseback-riding through the mountains and off-road Jeep tours.
Top attractions include the Out of Africa Wildlife Park – where you can also take on a zipline course – and the Verde Valley Archaeology Center. The latter looks at the life of the Native Sinagua people.
Great Camp Verde accommodation options include the Cliff Castle Casino Hotel and the Fort Verde Suites.

More Tucson road trips
Albuquerque to Tucson | Bisbee to Tucson | Casa Grande to Tucson | Chandler to Tucson | Tucson to Colorado Springs | Dallas to Tucson | Deming NM to Tucson | Tucson to Denver | El Paso to Tucson | Tucson to Flagstaff | Tucson to Grand Canyon (South Rim) | Houston to Tucson | Las Cruces to Tucson | Tucson to Mesa AZ | Phoenix to Tucson | Tucson to Prescott | Santa Fe to Tucson | Tucson to Scottsdale | Tempe to Tucson | Tucson to Tombstone | Yuma to Tucson.
More Sedona road trips
Albuquerque to Sedona | Denver to Sedona | Sedona to Grand Canyon (South Rim) | Mesa AZ to Sedona | Phoenix to Sedona | Prescott to Sedona | Sedona to Santa Fe | Scottsdale to Sedona | Williams AZ to Sedona AZ.