Tampa to Myrtle Beach road trip: Drive time, distance & best stops

Planning a Tampa to Myrtle Beach road trip itinerary

The Tampa to Myrtle Beach drive connects the west coast of Florida to the Atlantic coast of South Carolina.

Tampa is justifiably one of the most popular holiday destinations in Florida. It’s home to top attractions such as the Florida Aquarium, ZooTampa, the Adventure Island water park and Busch Gardens theme park.

Other great Tampa experiences include historic Ybor City food walking tours,  seeing the highlights in a street legal golf cart and a Haunted Tampa tour that combines ghosts and pubs.

Also on offer are Segway tours, history cruises, dolphin-watching and celebrity homes tours.

Tampa accommodation is best booked in advance – look for deals here.

Myrtle Beach is a beach resort city on the Atlantic coast of South Carolina. Good Myrtle Beach experiences include a history, movies and music trolley tour, guided kayaking adventures and Huntington Beach State Park Segway tour.

There are also several shows on offer. Try the Charles Bach Wonders show for magic, Legends in Concert for tribute acts and the Polynesian Fire Luau and Dinner Show for dancing and fire stunts.

It’s worth booking Myrtle Beach accommodation in advance. For the best deals, check here.

Tampa to Myrtle Beach distance and driving time

By car, the distance from Tampa to Myrtle Beach is 529 miles. You can expect a driving time of around eight hours and 44 minutes.

The best stops to add to a Tampa to Myrtle Beach road trip itinerary are Jacksonville, Savannah and Charleston.

For more suggestions, see the guides to the Savannah to Jacksonville drive and Jacksonville to Tampa drive.

Tampa to Myrtle Beach drive: Jacksonville, Florida

Top Jacksonville experiences include Amelia Island kayak tours, guided art and architecture tours by electric bike and electric skateboard rides along Fernandina Beach.

For cultural attractions, head to the Cummer Museum, where the strength tends to be the rotating temporary exhibitions.

Highly-rated Jacksonville accommodation options include the charming Riverdale Inn B&B and the conveniently downtown Hyatt Regency.

Best stops between Tampa and Myrtle Beach: Savannah, Georgia

Savannah has a timewarp handsomeness about it. Parks are lined by mossy oak trees, 19th century buildings ooze history and riverboats glide along the rivers.

Great activities in Savannah include the Ghosts and Gravestones trolley tourriverboat cruises and a true crime pub crawl.

Tampa to Myrtle Beach road trip attractions: Charleston SC

Charleston SC is one of the most attractive historic cities in the South.

Highlights of a visit include plantation tours – take your pick from the Boone Plantation and the Magnolia Plantation. Most visitors will also take the ferry to Fort Sumter, where the American Civil War started.

Other classic Charleston activities include a horse and carriage tour, history cruises on the harbor and night-time ghost walks.

For less conventional options, try a dinner cruise with live music, a Downtown food tour and a speakeasy cocktail-making class.

Ocean Boulevard in Myrtle Beach, South Carolina.
Ocean Boulevard in Myrtle Beach, South Carolina. Photo by Jeremy Kierez/ Unsplash.

More Myrtle Beach road trips

Asheville to Myrtle Beach | Atlanta to Myrtle Beach | Augusta GA to Myrtle Beach SC | Baltimore to Myrtle Beach | Boston to Myrtle Beach | Charlotte to Myrtle Beach | Columbia SC to Myrtle Beach | Fayetteville NC to Myrtle Beach | Greensboro to Myrtle Beach | Greenville to Myrtle Beach | Nashville to Myrtle Beach | New York City to Myrtle Beach | Orlando to Myrtle Beach | Philadelphia to Myrtle Beach | Pittsburgh to Myrtle Beach | Raleigh to Myrtle Beach | Spartanburg to Myrtle Beach | Washington DC to Myrtle Beach | Wilmington NC to Myrtle Beach.

More Tampa road trips

Asheville to Tampa | Atlanta to Tampa | Austin to Tampa | Baltimore to Tampa | Buffalo to Tampa | Charlotte to Tampa | Dallas to Tampa | Tampa to Daytona Beach | Tampa to Destin | Gainesville to Tampa | Houston to Tampa | Jacksonville to Tampa | Lakeland to Tampa | Memphis to Tampa | Nashville to Tampa | Tampa to New Orleans | Ocala to Tampa | Orlando to Tampa | Tampa to Panama City | Tampa to Pensacola | Philadelphia to Tampa | Pittsburgh to Tampa | Raleigh to Tampa | Tampa to St Augustine | St Louis to Tampa | Tallahassee to Tampa | Valdosta to Tampa | Washington DC to Tampa.