Pensacola to Biloxi drive: Best road trip stops, distance & time

Finding the best things to do between Pensacola and Biloxi

The drive from Pensacola to Biloxi takes you along the Gulf Coast from Florida to Mississippi.

The westernmost city on the Florida Panhandle, Pensacola is home to a major US Naval Station. But for most visitors, interest will lie in the white sand beaches and barrier islands.

Top Pensacola activities include nighttime kayaking with colourful LEDs lighting up the kayaks, and dolphin-watching cruises around the bay.

Other ways of exploring include downtown food tours, ghost and graveyard tours, guided pub crawls, Segway tours and sunset cruises.

For beachside Pensacola accommodation with great guest reviews, take a look at the Pensacola Beach Resort and the SpringHill Suites Pensacola Beach.

Biloxi on the Mississippi coast is best known as a casino destination, but there’s plenty to keep non-gamblers interested. The Biloxi Lighthouse opened in 1848, and is now open for public tours. The Maritime and Seafood Industry Museum covers the region’s history, and looks at just how big a business fishing is. You can also take a cruise on one of the schooners moored outside the museum.

Also in Biloxi is Beauvoir, the lavish home of Confederate president Jefferson Davis. The mansion is open for tours.

For Biloxi accommodation, try the Scarlet Pearl Casino Resort for entertainment and the South Beach Hotel and Suites for beachside location.

Pensacola to Biloxi distance and driving time

By car, the distance from Pensacola to Biloxi is 120 miles. That makes for a driving time of around one hour and 48 minutes. The quickest route is mostly along the I-10.

The best stops to add to a Pensacola to Biloxi road trip itinerary are Gulf Shores, Mobile and Pascagoula.

Pensacola to Biloxi road trip attractions: Gulf Shores, Alabama

Gulf Shores has a touch of the Margaritaville lifestyle, which should come as no surprise given Jimmy Buffett’s sister runs restaurant and music bar LuLu’s here.

A little soft adventure can be mixed in with the turquoise water, white sand and fun-loving bars, however. Top Gulf Shores experiences include kayaking with dolphins and paddleboarding with Pure Aloha Adventures.

Fabulous beachside accommodation in Gulf Shores include the Lodge at Gulf State Park and the Phoenix All Suites West Hotel.

Best stops between Pensacola and Biloxi: Mobile, Alabama

The Alabama Gulf Coast port city of Mobile has a perhaps unexpected party spirit. This is best explored in the bars, or at the Mobile Carnival Museum.

You can also head on board the USS Alabama battleship or visit the National Maritime Museum of the Gulf of Mexico. The latter includes a ship simulator, where you can have a go at steering a ship through the Gulf.

Mobile experience options include a downtown food tour and a wildlife kayaking tour.

Top Mobile accommodation picks include the personality-packed Fort Conde Inn and the riverside Renaissance Mobile Riverview Plaza.

Pensacola to Biloxi drive: Pascagoula MS

For most visitors, Pascagoula MS is mainly about the beach. But you can also venture inside the Round Island Lighthouse, which has been standing since 1859.

Even more historic is the LaPointe-Krebs House, which was built in 1757 and is the oldest building in the state. For bigger thrills, head to the Gulf Coast Gator Ranch. Here, airboat tours head over the alligator-filled swamps.

Find Pascagoula accommodation deals here.

Biloxi, Mississippi.
Biloxi, Mississippi. Photo by Lera Freeland/ Unsplash.

More Pensacola road trips

Atlanta to Pensacola | Birmingham AL to Pensacola | Dallas to Pensacola | Pensacola to Destin | Pensacola to Fort Lauderdale | Pensacola to Fort Walton Beach | Pensacola to Gulf Shores | Houston to Pensacola | Jacksonville to Pensacola | Memphis to Pensacola | Pensacola to Miami | Mobile to Pensacola | Nashville to Pensacola | Pensacola to New Orleans | Pensacola to Orange Beach | Pensacola to Panama City | Pensacola to Orlando | Tallahassee to Pensacola | Tampa to Pensacola.

More Biloxi road trips

Atlanta to Biloxi | Baton Rouge to Biloxi | Houston to Biloxi | Jackson MS to Biloxi | Memphis to Biloxi | Mobile to Biloxi | New Orleans to Biloxi.