Orlando to Port St Lucie drive: Best stops, distance & time
The best road trip stops on the Orlando to Port St Lucie drive are Kissimmee, Marsh Beast Airboat Tours and Vero Beach. The distance from Orlando to Port St Lucie by car is 125 miles, with a 2h driving time.
Planning an Orlando to Port St Lucie road trip itinerary
The Orlando to Port St Lucie drive connects Florida’s theme park capital to the east coast.
Orlando is known worldwide as the home of Disney World, but there’s far more to it than Mickey and Co. You can get crazy selfies at the Museum of Illusions or WonderWorks, learn how chocolate is made at Chocolate Kingdom and ride the Wheel at ICON Park or Orlando StarFlyer. Alternatively, visit Titanic: The Artifact Exhibition, play adventure golf at Pirates’ Cove and say hi to the stingrays at Sea Life.
In the evenings, there’s the Polynesian Fire Luau and Dinner Show, Cirque du Soleil’s Drawn To Life and the Outta Control magic comedy show.
Other Orlando experiences include glow-in-the-dark kayaking, foodie walking tours and kayaking through Cypress forest.
The secret to getting Orlando accommodation deals is flexibility. There are hundreds of hotels, and you’ll likely be driving everywhere anyway. So hunt down the cheapest rates, and don’t get too hung up on exact location.
Port St Lucie is a gentle place, with the main attraction being the Port St Lucie Botanical Gardens. Built around a fountain-dominated lake, there are separate rose, orchid and butterfly gardens. The other highlight is the 1,000ft boardwalk at the Port District, which runs along the St Lucie River, showing off the mangroves.
Stays in Port St Lucie can be cheaper than elsewhere along the coast. Accommodation picks include the Hilton Garden Inn and Homewood Suites.
Orlando to Port St Lucie distance and driving time
By car, the distance from Orlando to Port St Lucie is 125 miles. You can expect a driving time of around two hours. The quickest route is usually via Florida’s Turnpike.
The best stops to add to an Orlando to Port St Lucie road trip itinerary are Kissimmee, Marsh Beast Airboat Tours and Vero Beach.
Orlando to Port St Lucie drive: Kissimmee
Effectively a southern suburb of Orlando, family-friendly Kissimmee goes its own way. The Old Town Entertainment District, full of restaurants, bars and fairground-esque attractions, is the centerpiece.
Good Kissimmee experiences include airboat swamp tours, self-guided lakefront tours on an electrified adult trike and scenic helicopter flights over Florida’s theme parks.
Perhaps best of all, though, is a two hour eco-kayaking tour. This heads through the cypress forest on Shingle Creek – the headwaters of the Everglades.
Reliably good Kissimmee hotels include the Banana Bay Resort and the affordably retro Hotel Monte Carlo.
Orlando to Port St Lucie road trip attractions: Marsh Beast Airboat Tours
To the west of Vero Beach, Marsh Beast Airboat tours runs nature cruises through the marshlands. There’s a great chance of spotting alligators and turtles, while the boat captains are highly experienced and knowledgeable. The airboat rides go through the Blue Cypress Conservation Area.
Best stops between Orlando and Port St Lucie: Vero Beach
With beaches on the Atlantic side of the Indian River Lagoon, Vero Beach can be used as a sun and sand destination. But there’s more to it than that. The Vero Beach Museum of Art provides a culture fix and the McKee Botanical Garden showcases incredible floral diversity.
Fun Vero Beach activities include tiki cabana boat cruises and fat tire electric bike tours.
For Vero Beach accommodation picks, try the Prestige Hotel by the beach or the Hampton Inn downtown.

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