Houston to Santa Fe road trip: Best stops, distance & driving time

Planning a Houston to Santa Fe road trip itinerary

The Houston to Santa Fe drive takes you across the biggest city in Texas to the New Mexico capital.

The top Houston attraction is unquestionably the NASA Space Center, which takes you behind the scenes of the Johnson Space Center. This includes the Mission Briefing Center, and a vast array of high tech exhibitions.

Other attractions include the Houston Museum of Natural Science and the Children’s Museum

For more Houston experiences, try hip hop party bike tours, foodie walks in the Montrose neighbourhood and quirky tours of Houston’s tunnel system.

Top Houston accommodation options include the superb value Club Quarters Houston Downtown and the upscale but boutique Magnolia.

Santa Fe is one of the oldest cities in the US, and has a huge arts scene. The glut of adobe architecture makes the New Mexico capital highly photogenic. These buildings are best seen on an architecture walking tour.

Fab Santa Fe experiences include history walks covering the city’s past, on-the-move photography classes and New Mexican food tours through the evocative Santa Fe Plaza.

For other options, try small group e-bike tours through lesser-known areas of the city and ghost story tours.

If you want memorable Santa Fe accommodation, try the Hacienda in the Railyard Arts District or the adobe-style La Fonda on the Plaza.

Houston to Santa Fe distance and driving time

By car, the distance from Houston to Santa Fe is 874 miles. That makes for a driving time of around 13 hours and 12 minutes. The quickest route is along the I-45, US-287, I-40 and US-285.

The best stops to add to a Houston to Santa Fe road trip itinerary are Dallas, Amarillo TX and Santa Rosa NM.

For more ideas, check out the guides to individual sections of the drive:

Houston to Santa Fe drive: Dallas

Dallas has plenty of high quality cultural attractions. These include the Nasher Scupture Center, Pioneer Square and the Perot Museum of Science and Nature.

But for many visitors, the main reason to visit Dallas is the JFK assassination. Yes, you can go up to the Book Depository where Lee Harvey Oswald supposedly took his shot from.

Top Dallas experiences include a JFK Assassination and Museum tour, the GeO-Deck at Reunion Tower and a self-guided scavenger hunt.

Good places to stay in Dallas with a pool include the sassy Kimpton Pittman downtown and the historic Warwick Melrose near Turtle Creek.

The best way to combine the JFK sites in Dallas is a special themed tour. This takes in the JFK Memorial, Dealey Plaza and the Grassy Knoll before heading to Lee Harvey Oswald’s rooming house. It finishes in the Sixth Floor Museum of the Texas Book Depository. On the way, expert guides take you through the assassination facts and theories. Find out more here.

Best stops between Houston and Santa Fe: Amarillo TX

Amarillo is a classic stop on Route 66. Highlights include Cadillac Ranch, an art installation featuring 10 brightly-painted Cadillacs buried nose-first in the ground. You’ll also find the Texas Air and Space Museum here, and the American Quarter Horse Hall of Fame. For the great outdoors, Palo Duro Canyon State Park is just to the south-east of the city.

Interesting Amarillo activities include Route 66 walking tours and scavenger hunts.

For high quality Amarillo accommodation, try the historic Barfield or the spacious Embassy Suites Amarillo Downtown.

Houston to Santa Fe road trip attractions: Santa Rosa NM

Santa Rosa NM bills itself as the Scuba diving capital of the Southwest, largely thanks to the Blue Hole. This 81ft deep pool, fed by an artesian spring, is naturally heated to 62 degrees year-round. Divers need a permit, swimmers don’t.

Another alternative for swimming is Park Lake, which is patrolled by lifeguards in summer and has an inflatable obstacle course that’s very popular with children.

Car-lovers, meanwhile, can enjoy the Route 66 Auto Museum.

If stopping for the night, accommodation in Santa Rosa is all motel chains.

Adobe architecture in Santa Fe, New Mexico.
Adobe architecture in Santa Fe, New Mexico. Photo by Doni Rath/ Unsplash.

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