Greenville to Myrtle Beach drive: Best stops, distance & time

Planning a Greenville to Myrtle Beach road trip itinerary

The Greenville to Myrtle Beach drive takes you from one of South Carolina’s biggest cities to the coast.

Greenville SC is one of the fastest-growing cities in the US. It strikes a nice balance between outdoorsiness, culture and decadence. Falls Park on the Reedy brings cascades near the city center.  The Upcountry History Museum covers regional history. And the Roper Mountain Science Center has a planetarium, dinosaur adventure trail, butterfly garden and a living history farm.

Enjoyable Greenville experiences include craft cocktail tours, Segway adventures, paranormal walking tours and dessert-themed foodie tours.

Great Greenville accommodation choices include the spacious SpringHill Suites and the charming Pettigru Place Bed and Breakfast.

Myrtle Beach is a beach resort city on the Atlantic coast of South Carolina. Good Myrtle Beach experiences include a history, movies and music trolley tour, guided kayaking adventures and Huntington Beach State Park Segway tour.

There are also several shows on offer. Try the Charles Bach Wonders show for magic, Legends in Concert for tribute acts and the Polynesian Fire Luau and Dinner Show for dancing and fire stunts.

It’s worth booking Myrtle Beach accommodation in advance. For the best deals, check here.

Greenville to Myrtle Beach distance and driving time

By car, the distance from Greenville SC to Myrtle Beach SC is 252 miles. That makes for a driving time of around four hours.

The best stops to add to a Greenville to Myrtle Beach road trip itinerary are Clinton SC, Columbia SC and Florence SC.

Greenville to Myrtle Beach drive: Clinton SC

The Millers Fork Trail in Clinton SC is just off the I-26. It is short enough to be a handy journey-breaker. The mile-long, naturally-surfaced trail follows the Millers Fork stream through the forest, with a small series of cascades being the highlight. The Rose Hill Plantation State Historic Site and Battle of Musgrove Mill State Historic Site are also nearby.

Greenville to Myrtle Beach road trip attractions: Columbia SC

Columbia is the capital city of South Carolina. Top attractions include the South Carolina State Museum, which looks at the rich history of the state. It does so in a surprisingly fun way, with a digital planetarium and 4D theater.

But the city’s real appeal is in the numerous parks along the Broad River. These include the Riverbanks Zoo and Garden.

For well-rated Columbia accommodation options, try the academia-themed Graduate and the characterful Hotel Trundle.

Best stops between Greenville and Myrtle Beach: Florence SC

The Florence County Museum offers a good mix of science, art and history. But the Florence Veterans Park is arguably a more impressive cultural attraction. The six-acre park is dedicated to military veterans, and is dotted with grand sculptures and memorials.

Meanwhile, the Lynches River County Park to the south of the city is a popular spot for kayaking and canoeing. There’s also an Environmental Discovery Center, which aims to educate visitors about the local ecosystems.

Sunrise at Myrtle Beach, SC.
Sunrise at Myrtle Beach, SC. Photo by bootsbowsandbeaches/ Pixabay.

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