Greensboro NC to Greenville SC drive: Time, distance & best stops

Planning a Greensboro NC to Greenville SC road trip itinerary

The Greensboro NC to Greenville SC drive connects one of the biggest cities in North Carolina to one of the biggest cities in South Carolina.

Greensboro NC has a handful of strong cultural attractions. The first port of call should be the International Civil Rights Center and Museum, which houses the original FW Woolworth’s lunch counter. This was where four college freshmen staged a sit-in at the whites-only venue – a key moment of non-violent direct action in the Civil Rights struggle.

There are more backstories at the Greensboro History Museum, and the Guildford Courthouse National Military Park focuses on a Revolutionary War turning point.

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Greenville SC is one of the fastest-growing cities in the US. It strikes a nice balance between outdoorsiness, culture and decadence. Falls Park on the Reedy brings cascades near the city center.  The Upcountry History Museum covers regional history. And the Roper Mountain Science Center has a planetarium, dinosaur adventure trail, butterfly garden and a living history farm.

Enjoyable Greenville experiences include craft cocktail tours, Segway adventures, paranormal walking tours and dessert-themed foodie tours.

Great Greenville accommodation choices include the spacious SpringHill Suites and the charming Pettigru Place Bed and Breakfast.

Greensboro NC to Greenville SC distance and driving time

By car, the distance from Greensboro NC to Greenville SC is 189 miles. That makes for a driving time of around two hours and 54 minutes. The quickest route is along the I-85.

The best stops to add to a Greensboro NC to Greenville SC road trip itinerary are Salisbury NC, Charlotte NC and Spartanburg SC.

Greensboro NC to Greenville SC road trip attractions: Salisbury NC

Salisbury NC punches above its weight. The Hall House Museum shows off an 1820s building originally designed as classrooms, then turned into a sumptuous family home.  The Rowan Museum covers regional history. And the NC Transportation Museum offers a train station, roundhouse and plenty of vintage locomotive.

Best stops between Greensboro NC and Greenville SC: Charlotte NC

Charlotte is the biggest city in North Carolina. Major attractions include the NASCAR Hall of Fame, the thrill-packed Carowinds amusement park and the Billy Graham Library. Another popular option is the Sea Life aquarium.

For top Charlotte activities, try historical city tours by golf cart, Segway tours through the Uptown neighbourhood and after dark ghost tours.

Well-reviewed and central Charlotte accommodation options include the AC by Marriott and the Hyatt House.

Greensboro NC to Greenville SC: Spartanburg SC

Spartanburg SC is home to the Hub City Railroad Museum, inside the historic Southern Railway Spartanburg Union Depot. Here, you can watch passing trains from the observation deck and learn about the role of the railroads in South Carolina’s peach and textiles industries.

The city is also home to the BMW Zentrum Museum, at the BMW manufacturing plant. This offers a mixture of company history and classic cars. Otherwise, Spartanburg is a place of parks, with the Hatcher Garden and Woodland Preserve being the highlight.

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Greenville, South Carolina
Greenville, South Carolina. Photo by Ernest_Roy/ Pixabay.

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