Denver to Pittsburgh road trip: Best stops, distance & drive time

The best road trip stops on the Denver to Pittsburgh drive are Kansas City, St Louis and Indianapolis. The distance from Denver to Pittsburgh by car is 1,443 miles, with a 20h52m driving time.

Planning a Denver to Pittsburgh road trip itinerary

A Denver to Pittsburgh drive takes you from the capital of Colorado to the biggest city in western Pennsylvania.

Top Denver experiences include Rocky Mountain National Park day tours, downtown Denver food tours and chilling guided ghost walks around the Cheeseman Park cemetery.

Pittsburgh in western Pennsylvania is a monstrously underrated city, with a series of stellar attractions. Get great views from the top of the Duquesne Incline, enjoy the globally-themed rooms at the unmissable Cathedral of Learning and become immersed in pop art at the Warhol Museum.

You can explore Pittsburgh with a hop-on, hop-off bus pass. Pittsburgh experiences include bike tours full of stories, guided whiskey-themed walks and craft beer sampling on a multi-brewery tour.

To find good deals on Pittsburgh hotels, hunt here.

Denver to Pittsburgh distance and driving time

By car, the distance from Denver to Pittsburgh is 1,443 miles. That makes for a driving time of around 20 hours and 52 minutes.

For more ideas of things to do on the Denver to Pittsburgh drive, check out the guides to the individual sections of the road trip.

Best stops on a Denver to Pittsburgh road trip: Kansas City

Technically two cities spread over two different states, Kansas City has a rich cultural heritage. The Kemper Museum of Contemporary Art, Nelson-Atkins Museum of Art and American Jazz Museum show this off. Other top attractions include the National World I Memorial and the Negro Leagues Baseball Museum

Good experiences in Kansas City include an indulgent food tour of the city’s best BBQ joints, Segway tours, the Sealife Aquarium and wine-tasting trips.

Denver to Pittsburgh road trip attractions: St Louis

St Louis is one of America’s great crossroads cities. The major landmark is the 630ft-tall Gateway Arch, which visitors can go to the top of. Other top attractions include the Cathedral Basilica of St Louis, the Missouri Botanical Garden and Busch Stadium.

Good St Louis experiences include highlight-packed trolley tours, true crime walking tours and small group tours that include going to the top of the St Louis Arch and a Mississippi River cruise.

For St Louis accommodation with personality, try the Last Hotel or the Pennywell.