Boston to Greenville SC road trip: Best stops, drive time & distance

The best road trip stops on the Boston to Greenville SC drive are New York City, Washington DC and Durham NC. The distance from Boston to Greenville SC by car is 938miles, with an 14h45m driving time.

Planning a Boston to Greenville SC road trip itinerary

The Boston to Greenville SC drive connects the capital of Massachusetts to one of the biggest cities in South Carolina.

Boston is drenched in history, with the Boston Tea Party Ships and Museum a good first stop on the revolutionary trail. Other Boston attractions include the New England Aquarium, the View Boston observation deck and the Fenway Park baseball stadium.

There are also hundreds of Boston tour options, some more distinctive than others. Good choices include walking the Freedom Trail with a historian guide and story-packed tours of the Harvard campus. For a more Italian flavour, try a North End pizza and history tour. On a sunny day, try a sightseeing day sail around Boston Harbor.

If looking for the best Boston accommodation options, pick the Langham for luxury or the Lenox for a slice of cool in the Back Bay neighborhood. The Liberty, meanwhile, is a jaw-dropping conversion of a former prison.

Greenville SC is one of the fastest-growing cities in the US. It strikes a nice balance between outdoorsiness, culture and decadence. Falls Park on the Reedy brings cascades near the city center. The Upcountry History Museum covers regional history. And the Roper Mountain Science Center has a planetarium, dinosaur adventure trail, butterfly garden and a living history farm.

Enjoyable Greenville experiences include craft cocktail tours, Segway adventures, paranormal walking tours and dessert-themed foodie tours.

Great Greenville accommodation choices include the spacious SpringHill Suites and the charming Pettigru Place Bed and Breakfast.

Boston to Greenville SC distance and driving time

By car, the distance from Boston to Greenville SC is 938 miles. You can expect a driving time of around 14 hours and 45 minutes. The quickest route is via the I-90, I-84, I-91, I-95 and I-85.

The best stops to add to a Boston to Greenville SC road trip itinerary are New York City, Washington DC and Durham NC.

For more suggestions, check out the guides to the individual legs of the journey.

Best stops between Boston and Greenville SC: New York City

Highlights of New York City include the Empire State Building, the 9/11 Memorial Museum, the Museum of Modern Art and the American Museum of Natural History.

For great New York tours, try the boat trip to the Statue of Liberty and Ellis Island, a night time city lights helicopter flight and a Greenwich village food tour.

More unusual options include catacombs tours, a round-Manhattan architecture cruise and a guided exploration of Grand Central Station’s secrets.

You seriously need to shop around to find affordable New York City accommodation. Start looking for deals here.

Boston to Greenville SC road trip attractions: Washington DC

Washington DC has an enormous range of tours, experiences and attractions available. You could happily spend weeks in the Smithsonian Museums alone. Top choices, however, include the nighttime monuments and memorials tour, small group guided visits to the Capitol and National Library of Congress and Lincoln assassination tours that visit Fords Theatre.

Memorable Washington DC accommodation options include the Willard, where Martin Luther King Jr wrote his I Have A Dream speech. There’s also the Watergate Hotel, a luxurious conversion of the offices from the Watergate scandal.

Boston to Greenville SC drive: Durham NC

Durham NC is a big tech research center, and home to Duke University. The latter is home to the Nasher Museum of Art and the soaring Gothic Duke Chapel.

Nature-lovers can go walking through the Sarah P Duke Gardens and take a tour of the Duke Lemur Center. The biggest crowd-pleaser, however, is the Museum of Life and Science. There are several sections to this, both indoor and outdoor. It’s mainly button-pushing, kid-friendly science indoors and black bears, butterflies and red wolves outside.

The best-rated Durham NC accommodation options are the Washington Duke Inn and Golf Club and the Hampton Inn and Suites at the University Medical Center.